Mechanisms Causing Acantholysis in Pemphigus-Lessons from Human Skin

Pemphigus vulgaris (PV) is an autoimmune bullous skin disease caused primarily by autoantibodies (PV-IgG) against the desmosomal adhesion proteins desmoglein (Dsg)1 and Dsg3. PV patient lesions are characterized by flaccid blisters and ultrastructurally by defined hallmarks including a reduction in...

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Detalles Bibliográficos
Autores principales: Egu, Desalegn Tadesse, Schmitt, Thomas, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205406/
https://www.ncbi.nlm.nih.gov/pubmed/35720332
http://dx.doi.org/10.3389/fimmu.2022.884067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205406/
https://www.ncbi.nlm.nih.gov/pubmed/35720332
http://dx.doi.org/10.3389/fimmu.2022.884067

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