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Mathematical Modeling of Free Thyroxine Concentrations During Methimazole Treatment for Graves’ Disease: Development and Validation of a Computer-Aided Thyroid Treatment Method
BACKGROUND: Methimazole (MMI) is the first-line treatment for patients with Graves’ disease (GD). While there are empirical recommendations for initial MMI doses, there is no clear guidance for subsequent MMI dose titrations. We aimed to (a) develop a mathematical model capturing the dynamics of fre...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205409/ https://www.ncbi.nlm.nih.gov/pubmed/35721705 http://dx.doi.org/10.3389/fendo.2022.841888 |