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Mathematical Modeling of Free Thyroxine Concentrations During Methimazole Treatment for Graves’ Disease: Development and Validation of a Computer-Aided Thyroid Treatment Method

BACKGROUND: Methimazole (MMI) is the first-line treatment for patients with Graves’ disease (GD). While there are empirical recommendations for initial MMI doses, there is no clear guidance for subsequent MMI dose titrations. We aimed to (a) develop a mathematical model capturing the dynamics of fre...

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Detalles Bibliográficos
Autores principales: Theiler-Schwetz, Verena, Benninger, Thomas, Trummer, Christian, Pilz, Stefan, Reichhartinger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205409/
https://www.ncbi.nlm.nih.gov/pubmed/35721705
http://dx.doi.org/10.3389/fendo.2022.841888