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Astrocyte depletion alters extracellular matrix composition in the demyelinating phase of Theiler’s murine encephalomyelitis

Astrocytes produce extracellular matrix (ECM) glycoproteins contributing to the blood-brain barrier and regulating the immune response in the central nervous system (CNS). The aim of this study was to investigate the impact of astrocyte depletion upon the clinical outcome and the composition of ECM...

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Detalles Bibliográficos
Autores principales: Allnoch, Lisa, Leitzen, Eva, Zdora, Isabel, Baumgärtner, Wolfgang, Hansmann, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205503/
https://www.ncbi.nlm.nih.gov/pubmed/35714111
http://dx.doi.org/10.1371/journal.pone.0270239