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Identification of upstream transcription factor binding sites in orthologous genes using mixed Student’s t-test statistics
BACKGROUND: Transcription factor (TF) regulates the transcription of DNA to messenger RNA by binding to upstream sequence motifs. Identifying the locations of known motifs in whole genomes is computationally intensive. METHODOLOGY/PRINCIPAL FINDINGS: This study presents a computational tool, named “...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205514/ https://www.ncbi.nlm.nih.gov/pubmed/35671296 http://dx.doi.org/10.1371/journal.pcbi.1009773 |