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Identification of upstream transcription factor binding sites in orthologous genes using mixed Student’s t-test statistics

BACKGROUND: Transcription factor (TF) regulates the transcription of DNA to messenger RNA by binding to upstream sequence motifs. Identifying the locations of known motifs in whole genomes is computationally intensive. METHODOLOGY/PRINCIPAL FINDINGS: This study presents a computational tool, named “...

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Detalles Bibliográficos
Autores principales: Huang, Tinghua, Xiao, Hong, Tian, Qi, He, Zhen, Yuan, Cheng, Lin, Zezhao, Gao, Xuejun, Yao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205514/
https://www.ncbi.nlm.nih.gov/pubmed/35671296
http://dx.doi.org/10.1371/journal.pcbi.1009773