A mouse infection model and long-term lymphatic endothelium co-culture system to evaluate drugs against adult Brugia malayi

The development of new drugs targeting adult-stage lymphatic filarial nematodes is hindered by the lack of a robust long-term in vitro culture model. Testing potential direct-acting and anti-Wolbachia therapeutic candidates against adult lymphatic filariae in vitro requires their propagation via chr...

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Detalles Bibliográficos
Autores principales: Marriott, Amy E., Furlong Silva, Julio, Pionnier, Nicolas, Sjoberg, Hanna, Archer, John, Steven, Andrew, Kempf, Dale, Taylor, Mark J., Turner, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205518/
https://www.ncbi.nlm.nih.gov/pubmed/35671324
http://dx.doi.org/10.1371/journal.pntd.0010474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205518/
https://www.ncbi.nlm.nih.gov/pubmed/35671324
http://dx.doi.org/10.1371/journal.pntd.0010474

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