Development of a physiological insulin resistance model in human stem cell–derived adipocytes

Adipocytes are key regulators of human metabolism, and their dysfunction in insulin signaling is central to metabolic diseases including type II diabetes mellitus (T2D). However, the progression of insulin resistance into T2D is still poorly understood. This limited understanding is due, in part, to...

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Detalles Bibliográficos
Autores principales: Friesen, Max, Khalil, Andrew S., Barrasa, M. Inmaculada, Jeppesen, Jacob F., Mooney, David J., Jaenisch, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205586/
https://www.ncbi.nlm.nih.gov/pubmed/35714187
http://dx.doi.org/10.1126/sciadv.abn7298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205586/
https://www.ncbi.nlm.nih.gov/pubmed/35714187
http://dx.doi.org/10.1126/sciadv.abn7298

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