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Development of a physiological insulin resistance model in human stem cell–derived adipocytes
Adipocytes are key regulators of human metabolism, and their dysfunction in insulin signaling is central to metabolic diseases including type II diabetes mellitus (T2D). However, the progression of insulin resistance into T2D is still poorly understood. This limited understanding is due, in part, to...
Autores principales: | Friesen, Max, Khalil, Andrew S., Barrasa, M. Inmaculada, Jeppesen, Jacob F., Mooney, David J., Jaenisch, Rudolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205586/ https://www.ncbi.nlm.nih.gov/pubmed/35714187 http://dx.doi.org/10.1126/sciadv.abn7298 |
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