Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study

Amphotericin B, an antifungal drug with a long history of use, forms fungicidal ion-permeable channels across cell membranes. Using solid-state nuclear magnetic resonance spectroscopy and molecular dynamics simulations, we experimentally elucidated the three-dimensional structure of the molecular as...

Descripción completa

Detalles Bibliográficos
Autores principales: Umegawa, Yuichi, Yamamoto, Tomoya, Dixit, Mayank, Funahashi, Kosuke, Seo, Sangjae, Nakagawa, Yasuo, Suzuki, Taiga, Matsuoka, Shigeru, Tsuchikawa, Hiroshi, Hanashima, Shinya, Oishi, Tohru, Matsumori, Nobuaki, Shinoda, Wataru, Murata, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205587/
https://www.ncbi.nlm.nih.gov/pubmed/35714188
http://dx.doi.org/10.1126/sciadv.abo2658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205587/
https://www.ncbi.nlm.nih.gov/pubmed/35714188
http://dx.doi.org/10.1126/sciadv.abo2658

Ejemplares similares