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A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

BACKGROUND: The large inter-individual variability in immune-cell composition and function determines immune responses in general and susceptibility o immune-mediated diseases in particular. While much has been learned about the genetic variants relevant for type 1 diabetes (T1D), the pathophysiolog...

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Detalles Bibliográficos
Autores principales: Chu, Xiaojing, Janssen, Anna WM, Koenen, Hans, Chang, Linzhung, He, Xuehui, Joosten, Irma, Stienstra, Rinke, Kuijpers, Yunus, Wijmenga, Cisca, Xu, Cheng-Jian, Netea, Mihai G, Tack, Cees J, Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205632/
https://www.ncbi.nlm.nih.gov/pubmed/35638288
http://dx.doi.org/10.7554/eLife.73709