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A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes
BACKGROUND: The large inter-individual variability in immune-cell composition and function determines immune responses in general and susceptibility o immune-mediated diseases in particular. While much has been learned about the genetic variants relevant for type 1 diabetes (T1D), the pathophysiolog...
Autores principales: | Chu, Xiaojing, Janssen, Anna WM, Koenen, Hans, Chang, Linzhung, He, Xuehui, Joosten, Irma, Stienstra, Rinke, Kuijpers, Yunus, Wijmenga, Cisca, Xu, Cheng-Jian, Netea, Mihai G, Tack, Cees J, Li, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205632/ https://www.ncbi.nlm.nih.gov/pubmed/35638288 http://dx.doi.org/10.7554/eLife.73709 |
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