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A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η(1)-C(2)H(4)OMe)(DMSO)(phen)](+) (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells

NMR-based metabolomics is a very effective tool to assess the tumor response to drugs by providing insights for their mode of action. Recently, a novel Pt(II) complex, [Pt(ƞ(1)-C(2)H(4)OMe)(DMSO)(phen)](+) (phen =  1,10-phenanthroline), Pt-EtOMeSOphen, was synthesized and studied for its antitumor a...

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Detalles Bibliográficos
Autores principales: De Castro, Federica, Stefàno, Erika, De Luca, Erik, Muscella, Antonella, Marsigliante, Santo, Benedetti, Michele, Fanizzi, Francesco Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205715/
https://www.ncbi.nlm.nih.gov/pubmed/35721691
http://dx.doi.org/10.1155/2022/8932137