Inhibition of TRPA1 Ameliorates Periodontitis by Reducing Periodontal Ligament Cell Oxidative Stress and Apoptosis via PERK/eIF2α/ATF-4/CHOP Signal Pathway

OBJECTIVE: In periodontitis, excessive oxidative stress combined with subsequent apoptosis and cell death further exacerbated periodontium destruction. TRPA1, an important transient receptor potential (TRP) cation channel, may participate in the process. This study is aimed at exploring the role and...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Guo, Shujuan, Huang, Yanli, Wei, Xiuqun, Liu, Li, Huo, Fangjun, Huang, Ping, Wu, Yafei, Tian, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205716/
https://www.ncbi.nlm.nih.gov/pubmed/35720191
http://dx.doi.org/10.1155/2022/4107915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205716/
https://www.ncbi.nlm.nih.gov/pubmed/35720191
http://dx.doi.org/10.1155/2022/4107915

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