Transferability of genetic risk scores in African populations

The poor transferability of genetic risk scores (GRSs) derived from European ancestry data in diverse populations is a cause of concern. We set out to evaluate whether GRSs derived from data of African American individuals and multiancestry data perform better in sub-Saharan Africa (SSA) compared to...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamiza, Abram B., Toure, Sounkou M., Vujkovic, Marijana, Machipisa, Tafadzwa, Soremekun, Opeyemi S., Kintu, Christopher, Corpas, Manuel, Pirie, Fraser, Young, Elizabeth, Gill, Dipender, Sandhu, Manjinder S., Kaleebu, Pontiano, Nyirenda, Moffat, Motala, Ayesha A., Chikowore, Tinashe, Fatumo, Segun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205766/
https://www.ncbi.nlm.nih.gov/pubmed/35654908
http://dx.doi.org/10.1038/s41591-022-01835-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205766/
https://www.ncbi.nlm.nih.gov/pubmed/35654908
http://dx.doi.org/10.1038/s41591-022-01835-x

Ejemplares similares