Effects of TS-142, a novel dual orexin receptor antagonist, on sleep in patients with insomnia: a randomized, double-blind, placebo-controlled phase 2 study

RATIONALE: Novel compound with potent antagonistic activity against orexin receptors may be new treatment option for patients with insomnia. OBJECTIVE: The aim was to investigate the efficacy and safety of single oral doses of the dual orexin receptor antagonist TS-142 in patients with insomnia. MET...

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Detalles Bibliográficos
Autores principales: Uchiyama, Makoto, Kambe, Daiji, Imadera, Yumiko, Kajiyama, Yu, Ogo, Hiroki, Uchimura, Naohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205809/
https://www.ncbi.nlm.nih.gov/pubmed/35296912
http://dx.doi.org/10.1007/s00213-022-06089-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205809/
https://www.ncbi.nlm.nih.gov/pubmed/35296912
http://dx.doi.org/10.1007/s00213-022-06089-6

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