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A method to prevail false positive responses due to excess cations and viscous nature of Radiopharmaceuticals in Limulus Amebocyte Lysate Gel Clot test

OBJECTIVE(S): Bacterial endotoxin test (BET) for detection and quantification of endotoxin in radiopharmaceuticals (RPs), used for therapy or diagnosis, is prerequisite to administration in patients. Out of the two established methods used for this purpose (Kinetic Chromogenic Assay: KCM and Gel Clo...

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Detalles Bibliográficos
Autores principales: Mitra, Arpit, Lad, Sangita, Sahu, Sudeep, Kulkarni, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205850/
https://www.ncbi.nlm.nih.gov/pubmed/35800418
http://dx.doi.org/10.22038/AOJNMB.2021.59607.1416