Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency

The protective effect of estrogens against cortical bone loss is mediated via direct actions on mesenchymal cells, but functional evidence for the mediators of these effects has only recently begun to emerge. We report that the matrix metalloproteinase 13 (MMP13) is the highest up-regulated gene in...

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Detalles Bibliográficos
Autores principales: Ponte, Filipa, Kim, Ha-Neui, Warren, Aaron, Iyer, Srividhya, Han, Li, Mannen, Erin, Gomez-Acevedo, Horacio, Nookaew, Intawat, Almeida, Maria, Manolagas, Stavros C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205908/
https://www.ncbi.nlm.nih.gov/pubmed/35715555
http://dx.doi.org/10.1038/s41598-022-14470-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205908/
https://www.ncbi.nlm.nih.gov/pubmed/35715555
http://dx.doi.org/10.1038/s41598-022-14470-w

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