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ARID1A loss derepresses a group of human endogenous retrovirus-H loci to modulate BRD4-dependent transcription

Transposable elements (TEs) through evolutionary exaptation have become an integral part of the human genome, offering ample regulatory sequences and shaping chromatin 3D architecture. While the functional impacts of TE-derived sequences on early embryogenesis have been recognized, their roles in ma...

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Detalles Bibliográficos
Autores principales: Yu, Chunhong, Lei, Xiaoyun, Chen, Fang, Mao, Song, Lv, Lu, Liu, Honglu, Hu, Xueying, Wang, Runhan, Shen, Licong, Zhang, Na, Meng, Yang, Shen, Yunfan, Chen, Jiale, Li, Pishun, Huang, Shi, Lin, Changwei, Zhang, Zhuohua, Yuan, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205910/
https://www.ncbi.nlm.nih.gov/pubmed/35715442
http://dx.doi.org/10.1038/s41467-022-31197-4