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Addressing challenges with real-world synthetic control arms to demonstrate the comparative effectiveness of Pralsetinib in non-small cell lung cancer

As advanced non-small cell lung cancer (aNSCLC) is being increasingly divided into rare oncogene-driven subsets, conducting randomised trials becomes challenging. Using real-world data (RWD) to construct control arms for single-arm trials provides an option for comparative data. However, non-randomi...

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Detalles Bibliográficos
Autores principales: Popat, Sanjay, Liu, Stephen V., Scheuer, Nicolas, Hsu, Grace G., Lockhart, Alexandre, Ramagopalan, Sreeram V., Griesinger, Frank, Subbiah, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205915/
https://www.ncbi.nlm.nih.gov/pubmed/35715405
http://dx.doi.org/10.1038/s41467-022-30908-1