Mid-pregnancy poly(I:C) viral mimic disrupts placental ABC transporter expression and leads to long-term offspring motor and cognitive dysfunction

Limited information is available about the effect of mid-pregnancy viral infections on the placental expression of efflux transporters and offspring behavior. We hypothesized that maternal exposure to polyinosinic-polycytidylic acid [poly(I:C)], a synthetic double-stranded RNA viral mimic, would imp...

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Detalles Bibliográficos
Autores principales: Monteiro, V. R. S., Andrade, C. B. V., Gomes, H. R., Reginatto, M. W., Império, G. E., Fontes, K. N., Spiess, D. A., Rangel-Junior, W. S., Nascimento, V. M. O., Lima, C. O. S., Sousa, R. P. C., Bloise, F. F., Matthews, S. G., Bloise, E., Pimentel-Coelho, P. M., Ortiga-Carvalho, T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205917/
https://www.ncbi.nlm.nih.gov/pubmed/35715474
http://dx.doi.org/10.1038/s41598-022-14248-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205917/
https://www.ncbi.nlm.nih.gov/pubmed/35715474
http://dx.doi.org/10.1038/s41598-022-14248-0

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