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Mid-pregnancy poly(I:C) viral mimic disrupts placental ABC transporter expression and leads to long-term offspring motor and cognitive dysfunction
Limited information is available about the effect of mid-pregnancy viral infections on the placental expression of efflux transporters and offspring behavior. We hypothesized that maternal exposure to polyinosinic-polycytidylic acid [poly(I:C)], a synthetic double-stranded RNA viral mimic, would imp...
Autores principales: | Monteiro, V. R. S., Andrade, C. B. V., Gomes, H. R., Reginatto, M. W., Império, G. E., Fontes, K. N., Spiess, D. A., Rangel-Junior, W. S., Nascimento, V. M. O., Lima, C. O. S., Sousa, R. P. C., Bloise, F. F., Matthews, S. G., Bloise, E., Pimentel-Coelho, P. M., Ortiga-Carvalho, T. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205917/ https://www.ncbi.nlm.nih.gov/pubmed/35715474 http://dx.doi.org/10.1038/s41598-022-14248-0 |
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