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Bifurcation drives the evolution of assembly-line biosynthesis
Reprogramming biosynthetic assembly-lines is a topic of intense interest. This is unsurprising as the scaffolds of most antibiotics in current clinical use are produced by such pathways. The modular nature of assembly-lines provides a direct relationship between the sequence of enzymatic domains and...
Autores principales: | Booth, Thomas J., Bozhüyük, Kenan A. J., Liston, Jonathon D., Batey, Sibyl F. D., Lacey, Ernest, Wilkinson, Barrie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205934/ https://www.ncbi.nlm.nih.gov/pubmed/35715397 http://dx.doi.org/10.1038/s41467-022-30950-z |
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