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Influences of social uncertainty and serotonin on gambling decisions
In many instances in life, our decisions’ outcomes hinge on someone else’s choices (i.e., under social uncertainty). Behavioral and pharmacological work has previously focused on different types of uncertainty, such as risk and ambiguity, but not so much on risk behaviors under social uncertainty. H...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205937/ https://www.ncbi.nlm.nih.gov/pubmed/35715450 http://dx.doi.org/10.1038/s41598-022-13778-x |
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author | Bellucci, Gabriele Münte, Thomas F. Park, Soyoung Q. |
author_facet | Bellucci, Gabriele Münte, Thomas F. Park, Soyoung Q. |
author_sort | Bellucci, Gabriele |
collection | PubMed |
description | In many instances in life, our decisions’ outcomes hinge on someone else’s choices (i.e., under social uncertainty). Behavioral and pharmacological work has previously focused on different types of uncertainty, such as risk and ambiguity, but not so much on risk behaviors under social uncertainty. Here, in two different studies using a double-blind, placebo-controlled, within-subject design, we administrated citalopram (a selective-serotonin-reuptake inhibitor) to male participants and investigated decisions in a gambling task under social and nonsocial uncertainty. In the social condition, gamble outcomes were determined by another participant. In the nonsocial condition, gamble outcomes were determined by a coin toss. We observed increased gamble acceptance under social uncertainty, especially for gambles with lower gains and higher losses, which might be indicative of a positivity bias in social expectations in conditions of high uncertainty about others’ behaviors. A similar effect was found for citalopram, which increased overall acceptance behavior for gambles irrespective of the source of uncertainty (social/nonsocial). These results provide insights into the cognitive and neurochemical processes underlying decisions under social uncertainty, with implications for research in risk-taking behaviors in healthy and clinical populations. |
format | Online Article Text |
id | pubmed-9205937 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92059372022-06-19 Influences of social uncertainty and serotonin on gambling decisions Bellucci, Gabriele Münte, Thomas F. Park, Soyoung Q. Sci Rep Article In many instances in life, our decisions’ outcomes hinge on someone else’s choices (i.e., under social uncertainty). Behavioral and pharmacological work has previously focused on different types of uncertainty, such as risk and ambiguity, but not so much on risk behaviors under social uncertainty. Here, in two different studies using a double-blind, placebo-controlled, within-subject design, we administrated citalopram (a selective-serotonin-reuptake inhibitor) to male participants and investigated decisions in a gambling task under social and nonsocial uncertainty. In the social condition, gamble outcomes were determined by another participant. In the nonsocial condition, gamble outcomes were determined by a coin toss. We observed increased gamble acceptance under social uncertainty, especially for gambles with lower gains and higher losses, which might be indicative of a positivity bias in social expectations in conditions of high uncertainty about others’ behaviors. A similar effect was found for citalopram, which increased overall acceptance behavior for gambles irrespective of the source of uncertainty (social/nonsocial). These results provide insights into the cognitive and neurochemical processes underlying decisions under social uncertainty, with implications for research in risk-taking behaviors in healthy and clinical populations. Nature Publishing Group UK 2022-06-17 /pmc/articles/PMC9205937/ /pubmed/35715450 http://dx.doi.org/10.1038/s41598-022-13778-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Bellucci, Gabriele Münte, Thomas F. Park, Soyoung Q. Influences of social uncertainty and serotonin on gambling decisions |
title | Influences of social uncertainty and serotonin on gambling decisions |
title_full | Influences of social uncertainty and serotonin on gambling decisions |
title_fullStr | Influences of social uncertainty and serotonin on gambling decisions |
title_full_unstemmed | Influences of social uncertainty and serotonin on gambling decisions |
title_short | Influences of social uncertainty and serotonin on gambling decisions |
title_sort | influences of social uncertainty and serotonin on gambling decisions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205937/ https://www.ncbi.nlm.nih.gov/pubmed/35715450 http://dx.doi.org/10.1038/s41598-022-13778-x |
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