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3D structure and in situ arrangements of CatSper channel in the sperm flagellum
The sperm calcium channel CatSper plays a central role in successful fertilization as a primary Ca(2+) gateway. Here, we applied cryo-electron tomography to visualize the higher-order organization of the native CatSper complex in intact mammalian sperm. The repeating CatSper units form long zigzag-r...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205950/ https://www.ncbi.nlm.nih.gov/pubmed/35715406 http://dx.doi.org/10.1038/s41467-022-31050-8 |