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3D structure and in situ arrangements of CatSper channel in the sperm flagellum

The sperm calcium channel CatSper plays a central role in successful fertilization as a primary Ca(2+) gateway. Here, we applied cryo-electron tomography to visualize the higher-order organization of the native CatSper complex in intact mammalian sperm. The repeating CatSper units form long zigzag-r...

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Detalles Bibliográficos
Autores principales:	Zhao, Yanhe, Wang, Huafeng, Wiesehoefer, Caroline, Shah, Naman B., Reetz, Evan, Hwang, Jae Yeon, Huang, Xiaofang, Wang, Tse-en, Lishko, Polina V., Davies, Karen M., Wennemuth, Gunther, Nicastro, Daniela, Chung, Jean-Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9205950/ https://www.ncbi.nlm.nih.gov/pubmed/35715406 http://dx.doi.org/10.1038/s41467-022-31050-8

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