Nintedanib regulates intestinal smooth muscle hyperplasia and phenotype in vitro and in TNBS colitis in vivo

Chronic inflammation of the human intestine in Crohn’s disease (CD) causes bowel wall thickening, which typically progresses to stricturing and a recurrent need for surgery. Current therapies have limited success and CD remains idiopathic and incurable. Recent evidence shows a key role of intestinal...

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Detalles Bibliográficos
Autores principales: Kataria, Jay, Kerr, Jack, Lourenssen, Sandra R., Blennerhassett, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206006/
https://www.ncbi.nlm.nih.gov/pubmed/35715562
http://dx.doi.org/10.1038/s41598-022-14491-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206006/
https://www.ncbi.nlm.nih.gov/pubmed/35715562
http://dx.doi.org/10.1038/s41598-022-14491-5

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