Streamlined and quantitative detection of chimerism using digital PCR

Animal chimeras are widely used for biomedical discoveries, from developmental biology to cancer research. However, the accurate quantitation of mixed cell types in chimeric and mosaic tissues is complicated by sample preparation bias, transgenic silencing, phenotypic similarity, and low-throughput...

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Detalles Bibliográficos
Autores principales: Suchy, Fabian P., Nishimura, Toshiya, Seki, Shinsuke, Wilkinson, Adam C., Higuchi, Maimi, Hsu, Ian, Zhang, Jinyu, Bhadury, Joydeep, Nakauchi, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206010/
https://www.ncbi.nlm.nih.gov/pubmed/35715477
http://dx.doi.org/10.1038/s41598-022-14467-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206010/
https://www.ncbi.nlm.nih.gov/pubmed/35715477
http://dx.doi.org/10.1038/s41598-022-14467-5

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