TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy

Ion fluxes across the inner mitochondrial membrane control mitochondrial volume, energy production, and apoptosis. TMBIM5, a highly conserved protein with homology to putative pH-dependent ion channels, is involved in the maintenance of mitochondrial cristae architecture, ATP production, and apoptos...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Dietsche, Felicia, Seitaj, Bruno, Rojas-Charry, Liliana, Latchman, Nadina, Tomar, Dhanendra, Wüst, Rob CI, Nickel, Alexander, Frauenknecht, Katrin BM, Schoser, Benedikt, Schumann, Sven, Schmeisser, Michael J, vom Berg, Johannes, Buch, Thorsten, Finger, Stefanie, Wenzel, Philip, Maack, Christoph, Elrod, John W, Parys, Jan B, Bultynck, Geert, Methner, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206080/
https://www.ncbi.nlm.nih.gov/pubmed/35715207
http://dx.doi.org/10.26508/lsa.202201478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206080/
https://www.ncbi.nlm.nih.gov/pubmed/35715207
http://dx.doi.org/10.26508/lsa.202201478

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