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Investigation of BRCAness associated miRNA-gene axes in breast cancer: cell-free miR-182-5p as a potential expression signature of BRCAness

The concept of the ‘BRCAness’ phenotype implies the properties that some sporadic breast cancers (BC) share with BRCA1/2-mutation carriers with hereditary BC. Breast tumors with BRCAness have deficiencies in homologous recombination repair (HRR), like BRCA1/2-mutation carriers, and consequently coul...

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Detalles Bibliográficos
Autores principales: Darbeheshti, Farzaneh, Kadkhoda, Sepideh, Keshavarz-Fathi, Mahsa, Razi, Sepideh, Bahramy, Afshin, Mansoori, Yaser, Rezaei, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206264/
https://www.ncbi.nlm.nih.gov/pubmed/35715772
http://dx.doi.org/10.1186/s12885-022-09761-4