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Molecular epidemiological study of germline APC variant associated with hereditary gastrointestinal polyposis in dogs: current frequency in Jack Russell Terriers in Japan and breed distribution

BACKGROUND: Cases of gastrointestinal (GI) neoplastic polyps in Jack Russell Terriers (JRTs) have increased in Japan since the late 2000s. We recently demonstrated that JRTs with GI polyps heterozygously harbor an identical germline variant in the adenomatous polyposis coli (APC) gene, c.[462_463del...

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Detalles Bibliográficos
Autores principales: Yoshizaki, Kyoko, Hirata, Akihiro, Matsushita, Hiroyuki, Sakaguchi, Masahiro, Yoneji, Wakana, Owaki, Keishi, Sakai, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206296/
https://www.ncbi.nlm.nih.gov/pubmed/35717217
http://dx.doi.org/10.1186/s12917-022-03338-w