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Molecular epidemiological study of germline APC variant associated with hereditary gastrointestinal polyposis in dogs: current frequency in Jack Russell Terriers in Japan and breed distribution
BACKGROUND: Cases of gastrointestinal (GI) neoplastic polyps in Jack Russell Terriers (JRTs) have increased in Japan since the late 2000s. We recently demonstrated that JRTs with GI polyps heterozygously harbor an identical germline variant in the adenomatous polyposis coli (APC) gene, c.[462_463del...
Autores principales: | Yoshizaki, Kyoko, Hirata, Akihiro, Matsushita, Hiroyuki, Sakaguchi, Masahiro, Yoneji, Wakana, Owaki, Keishi, Sakai, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206296/ https://www.ncbi.nlm.nih.gov/pubmed/35717217 http://dx.doi.org/10.1186/s12917-022-03338-w |
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