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Normalization of gene expression data revisited: the three viewpoints of the transcriptome in human skeletal muscle undergoing load-induced hypertrophy and why they matter

BACKGROUND: The biological relevance and accuracy of gene expression data depend on the adequacy of data normalization. This is both due to its role in resolving and accounting for technical variation and errors, and its defining role in shaping the viewpoint of biological interpretations. Still, th...

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Detalles Bibliográficos
Autores principales: Khan, Yusuf, Hammarström, Daniel, Ellefsen, Stian, Ahmad, Rafi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206305/
https://www.ncbi.nlm.nih.gov/pubmed/35717158
http://dx.doi.org/10.1186/s12859-022-04791-y