Cargando…

Antitumor activity of recombinant oncolytic vaccinia virus with human IL2

The tumor microenvironment is highly immunosuppressive. The genetically modified oncolytic vaccinia virus (OVV) is a promising vector for cancer immunotherapy. The aim of the present study was to assess the antitumor effects of human interleukin-2 (hIL2)-armed OVV in vitro. The hIL2 gene was inserte...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Liqiong, Li, Huiqun, Xu, Qinggang, Wu, Yan, Chen, Dongfeng, Yu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206501/
https://www.ncbi.nlm.nih.gov/pubmed/35799600
http://dx.doi.org/10.1515/med-2022-0496