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PPARγ alleviates peritoneal fibrosis progression along with promoting GLUT1 expression and suppressing peritoneal mesothelial cell proliferation

OBJECTIVE: Peritoneal fibrosis (PF) is commonly induced by bioincompatible dialysate exposure during peritoneal dialysis, but the underlying mechanisms remain elusive. This study aimed to investigate the roles of peroxisome proliferator-activated receptor gamma (PPARγ) in PF pathogenesis. METHODS: R...

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Detalles Bibliográficos
Autores principales: Feng, Junxia, Lu, Meizhi, Li, Wenhao, Li, Jingchun, Meng, Ping, Li, Zukai, Gao, Xuejuan, Zhang, Yunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206601/
https://www.ncbi.nlm.nih.gov/pubmed/35380292
http://dx.doi.org/10.1007/s11010-022-04419-y