The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells

Maintenance of replication fork stability is essential for genome preservation. Stalled replication forks can be reversed by translocases such as SMARCAL1, and unless protected through the activity of the BRCA pathway, are subsequently subjected to nucleolytic degradation. The ATM and ATR kinases ar...

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Detalles Bibliográficos
Autores principales: Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Khatib, Jude B., Nicolae, Claudia M., Moldovan, George-Lucian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206655/
https://www.ncbi.nlm.nih.gov/pubmed/35717336
http://dx.doi.org/10.1038/s41389-022-00410-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206655/
https://www.ncbi.nlm.nih.gov/pubmed/35717336
http://dx.doi.org/10.1038/s41389-022-00410-w

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