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Polyphenols from persimmon fruit attenuate acetaldehyde-induced DNA double-strand breaks by scavenging acetaldehyde

Acetaldehyde, a metabolic product of ethanol, induces DNA damage and genome instability. Accumulation of acetaldehyde due to alcohol consumption or aldehyde dehydrogenase (ALDH2) deficiency increases the risks of various types of cancers, including esophageal cancer. Although acetaldehyde chemically...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Kenichiro, Kumatoriya, Kenji, Tando, Mizuki, Kometani, Takashi, Shinohara, Miki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206672/
https://www.ncbi.nlm.nih.gov/pubmed/35717470
http://dx.doi.org/10.1038/s41598-022-14374-9