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Polyphenols from persimmon fruit attenuate acetaldehyde-induced DNA double-strand breaks by scavenging acetaldehyde
Acetaldehyde, a metabolic product of ethanol, induces DNA damage and genome instability. Accumulation of acetaldehyde due to alcohol consumption or aldehyde dehydrogenase (ALDH2) deficiency increases the risks of various types of cancers, including esophageal cancer. Although acetaldehyde chemically...
Autores principales: | Matsuzaki, Kenichiro, Kumatoriya, Kenji, Tando, Mizuki, Kometani, Takashi, Shinohara, Miki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206672/ https://www.ncbi.nlm.nih.gov/pubmed/35717470 http://dx.doi.org/10.1038/s41598-022-14374-9 |
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