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Enucleated human mesenchymal stromal cells for the homing and the delivery of therapeutic cargos in vivo

The targeted delivery of therapeutics to diseased tissue enhances their efficacy and decreases their side effects. Here, we report enucleated mesenchymal stromal cells (MSC) as vehicles for the targeted delivery of therapeutic compounds. The cell nuclei are removed by density gradient centrifugation...

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Detalles Bibliográficos
Autores principales: Wang, Huawei, Alarcón, Christina N., Liu, Bei, Watson, Felicia, Searles, Stephen, Lee, Calvin K., Keys, Jeremy, Pi, Willie, Allen, Dale, Lammerding, Jan, Bui, Jack D., Klemke, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207157/
https://www.ncbi.nlm.nih.gov/pubmed/34931077
http://dx.doi.org/10.1038/s41551-021-00815-9