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Enucleated human mesenchymal stromal cells for the homing and the delivery of therapeutic cargos in vivo
The targeted delivery of therapeutics to diseased tissue enhances their efficacy and decreases their side effects. Here, we report enucleated mesenchymal stromal cells (MSC) as vehicles for the targeted delivery of therapeutic compounds. The cell nuclei are removed by density gradient centrifugation...
Autores principales: | Wang, Huawei, Alarcón, Christina N., Liu, Bei, Watson, Felicia, Searles, Stephen, Lee, Calvin K., Keys, Jeremy, Pi, Willie, Allen, Dale, Lammerding, Jan, Bui, Jack D., Klemke, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207157/ https://www.ncbi.nlm.nih.gov/pubmed/34931077 http://dx.doi.org/10.1038/s41551-021-00815-9 |
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