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Transduction of Systemically Administered Adeno-Associated Virus in the Colonic Enteric Nervous System and c-Kit Cells of Adult Mice

Systemic delivery of adeno-associated virus (AAV) vectors transduces the enteric nervous system. However, less is known on the mapping and morphological and neurochemical characterization in the adult mouse colon. We used AAV9-CAG-GFP (AAV9) and AAV-PHP.S-hSyn1-tdTomato farnesylated (PHP.S-tdTf) to...

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Detalles Bibliográficos
Autores principales: Wang, Lixin, Yuan, Pu-Qing, Challis, Collin, Ravindra Kumar, Sripriya, Taché, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207206/
https://www.ncbi.nlm.nih.gov/pubmed/35734536
http://dx.doi.org/10.3389/fnana.2022.884280