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Photoacoustic imaging reveals mechanisms of rapid-acting insulin formulations dynamics at the injection site

OBJECTIVE: Ultra-rapid insulin formulations control postprandial hyperglycemia; however, inadequate understanding of injection site absorption mechanisms is limiting further advancement. We used photoacoustic imaging to investigate the injection site dynamics of dye-labeled insulin lispro in the Hum...

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Detalles Bibliográficos
Autores principales: Khadria, Anjul, Paavola, Chad D., Maslov, Konstantin, Valenzuela, Francisco A., Sperry, Andrea E., Cox, Amy L., Cao, Rui, Shi, Junhui, Brown-Augsburger, Patricia L., Lozano, Emmanuel, Blankenship, Ross L., Majumdar, Ranajoy, Bradley, Scott A., Beals, John M., Oladipupo, Sunday S., Wang, Lihong V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207296/
https://www.ncbi.nlm.nih.gov/pubmed/35671972
http://dx.doi.org/10.1016/j.molmet.2022.101522