In vivo Proximity Labeling of Nuclear and Nucleolar Proteins by a Stably Expressed, DNA Damage-Responsive NONO-APEX2 Fusion Protein

Cellular stress can induce DNA lesions that threaten the stability of genes. The DNA damage response (DDR) recognises and repairs broken DNA to maintain genome stability. Intriguingly, components of nuclear paraspeckles like the non-POU domain containing octamer-binding protein (NONO) participate in...

Descripción completa

Detalles Bibliográficos
Autores principales: Trifault, Barbara, Mamontova, Victoria, Burger, Kaspar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207311/
https://www.ncbi.nlm.nih.gov/pubmed/35733943
http://dx.doi.org/10.3389/fmolb.2022.914873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207311/
https://www.ncbi.nlm.nih.gov/pubmed/35733943
http://dx.doi.org/10.3389/fmolb.2022.914873

Ejemplares similares