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Dysregulation of Astrocytic Glutamine Transport in Acute Hyperammonemic Brain Edema

Acute liver failure (ALF) impairs ammonia clearance from blood, which gives rise to acute hyperammonemia and increased ammonia accumulation in the brain. Since in brain glutamine synthesis is the only route of ammonia detoxification, hyperammonemia is as a rule associated with increased brain glutam...

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Detalles Bibliográficos
Autores principales: Zielińska, Magdalena, Albrecht, Jan, Popek, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207324/
https://www.ncbi.nlm.nih.gov/pubmed/35733937
http://dx.doi.org/10.3389/fnins.2022.874750