Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition

Thymocyte selection-associated high mobility group box (TOX) has been described to be a key regulator in the formation of CD8+ T cell exhaustion. Hepatitis C virus (HCV) infection with different lengths of antigen exposure in acute, chronic, and after resolution of HCV infection is the ideal immunol...

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Detalles Bibliográficos
Autores principales: Wildner, Nils H., Walker, Andreas, Brauneck, Franziska, Ditt, Vanessa, Peine, Sven, Huber, Samuel, Haag, Friedrich, Beisel, Claudia, Timm, Joerg, Schulze zur Wiesch, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207347/
https://www.ncbi.nlm.nih.gov/pubmed/35734162
http://dx.doi.org/10.3389/fimmu.2022.886646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207347/
https://www.ncbi.nlm.nih.gov/pubmed/35734162
http://dx.doi.org/10.3389/fimmu.2022.886646

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