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Insufficiency of hepatocyte growth factor activator inhibitor‐1 confers lymphatic invasion of tongue carcinoma cells

Hepatocyte growth factor (HGF) activator inhibitor type‐1 (HAI‐1), encoded by the SPINT1 gene, is a transmembrane protease inhibitor that regulates membrane‐anchored serine proteases, particularly matriptase. Here, we explored the role of HAI‐1 in tongue squamous cell carcinoma (TSCC) cells. An immu...

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Detalles Bibliográficos
Autores principales: Izumi, Aya, Yamamoto, Koji, Kawaguchi, Makiko, Yamashita, Fumiki, Fukushima, Tsuyoshi, Kiwaki, Takumi, Tanaka, Hiroyuki, Yamashita, Yoshihiro, Kataoka, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207362/
https://www.ncbi.nlm.nih.gov/pubmed/35332604
http://dx.doi.org/10.1111/cas.15346