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Bile Salt Hydrolase Degrades β-Lactam Antibiotics and Confers Antibiotic Resistance on Lactobacillus paragasseri

Bile salt hydrolase (BSH) is a well-characterized probiotic enzyme associated with bile detoxification and colonization of lactic acid bacteria in the human gastrointestinal tract. Here, we isolated a putative BSH (LpBSH) from the probiotic bacterium Lactobacillus paragasseri JCM 5343(T) and demonst...

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Detalles Bibliográficos
Autores principales: Kusada, Hiroyuki, Arita, Masanori, Tohno, Masanori, Tamaki, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207391/
https://www.ncbi.nlm.nih.gov/pubmed/35733973
http://dx.doi.org/10.3389/fmicb.2022.858263