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Peptidylarginine Deiminase 2 Autoantibodies Are Linked to Less Severe Disease in Multiple Sclerosis and Post-treatment Lyme Disease

BACKGROUND: Peptidylarginine deiminase 2 (PAD2) mediates the post-translational conversion of arginine residues in proteins to citrullines and is highly expressed in the central nervous system (CNS). Dysregulated PAD2 activity has been implicated in the pathogenesis of several neurologic diseases, i...

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Detalles Bibliográficos
Autores principales: Kim, Yaewon, Rebman, Alison W., Johnson, Tory P., Wang, Hong, Yang, Ting, Colantuoni, Carlo, Bhargava, Pavan, Levy, Michael, Calabresi, Peter A., Aucott, John N., Soloski, Mark J., Darrah, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207393/
https://www.ncbi.nlm.nih.gov/pubmed/35734473
http://dx.doi.org/10.3389/fneur.2022.874211