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Technical Performance Evaluation of Olink Proximity Extension Assay for Blood-Based Biomarker Discovery in Longitudinal Studies of Alzheimer's Disease

The core Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarkers; amyloid-β (Aß), total tau (t-tau), and phosphorylated tau (p-tau181), are strong indicators of the presence of AD pathology, but do not correlate well with disease progression, and can be difficult to implement in longitudi...

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Detalles Bibliográficos
Autores principales: Carlyle, Becky C., Kitchen, Robert R., Mattingly, Zoe, Celia, Amanda M., Trombetta, Bianca A., Das, Sudeshna, Hyman, Bradley T., Kivisäkk, Pia, Arnold, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207419/
https://www.ncbi.nlm.nih.gov/pubmed/35734478
http://dx.doi.org/10.3389/fneur.2022.889647