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Identification of Crucial Amino Acid Residues for Antimicrobial Activity of Angiogenin 4 and Its Modulation of Gut Microbiota in Mice

Angiogenin 4 bearing ribonuclease activity is an endogenous antimicrobial protein expressed in small and large intestine. However, the crucial amino acid residues responsible for the antibacterial activity of Ang4 and its impact on gut microbiota remain unknown. Here, we report the contribution of c...

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Detalles Bibliográficos
Autores principales: Sultana, Mst. Farzana, Suzuki, Maki, Yamasaki, Fumiya, Kubota, Wataru, Takahashi, Kohta, Abo, Hirohito, Kawashima, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207454/
https://www.ncbi.nlm.nih.gov/pubmed/35733962
http://dx.doi.org/10.3389/fmicb.2022.900948