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A Sparse Mixture-of-Experts Model With Screening of Genetic Associations to Guide Disease Subtyping

Motivation: Identifying new genetic associations in non-Mendelian complex diseases is an increasingly difficult challenge. These diseases sometimes appear to have a significant component of heritability requiring explanation, and this missing heritability may be due to the existence of subtypes invo...

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Detalles Bibliográficos
Autores principales: Courbariaux, Marie, De Santiago, Kylliann, Dalmasso, Cyril, Danjou, Fabrice, Bekadar, Samir, Corvol, Jean-Christophe, Martinez, Maria, Szafranski, Marie, Ambroise, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207464/
https://www.ncbi.nlm.nih.gov/pubmed/35734430
http://dx.doi.org/10.3389/fgene.2022.859462