HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing

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Recent advances in CRISPR-Cas9 techniques, especially the discovery of base and prime editing, have significantly improved our ability to make precise changes in the genome. We hypothesized that modulating certain endogenous pathway cells could improve the action of those editing tools in mammalian...

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Detalles Bibliográficos
Autores principales: Liu, Nan, Zhou, Lifang, Lin, Guifeng, Hu, Yun, Jiao, Yaoge, Wang, Yanhong, Liu, Jingming, Yang, Shengyong, Yao, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207553/
https://www.ncbi.nlm.nih.gov/pubmed/35784015
http://dx.doi.org/10.1016/j.omtn.2022.05.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207553/
https://www.ncbi.nlm.nih.gov/pubmed/35784015
http://dx.doi.org/10.1016/j.omtn.2022.05.036

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